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Oxygenating Trio® Treatment Protocol

Treatment Protocol

This advanced, pro-B vitamin-rich treatment paired with an oxygen-boosting application works to deliver oxygen into the skin while also fighting common signs of aging. The oxygen-boosting application provides quick and effective penetration, skin-plumping action, and a reduction of fine lines and wrinkles.

Oxygenating Trio®: Step 1 Activator (1.68 fl oz/50mL); Step 2 Detoxifier (1.68 fl oz/50mL); Step 3 Oxygenator (1.68 fl oz/47.6 g)

Key Ingredients

  • Hydrolyzed Candida Saitoana Extract is a type of fungi that encourages skin cell autophagy (the skin’s natural detoxification process). Studies show that topical application rids the skin cells of toxins and reduces free radical damage.
  • Methyl Perfluorobutyl Ether and Methyl Perfluoroisobutyl Ether a unique ingredient blend that interacts with the water in the skin, leading to evaporation and oxygen production. These unique compounds react with other ingredients in the formula to infuse the skin with oxygen and encourage circulation.
  • Niacinamide is a form of the B vitamin, niacin (vitamin B3). When used topically it has been shown to help reduce breakouts, rosacea-like symptoms, and the yellowing of the skin due to glycation and melanosome transfer. Niacinamide does not have the flushing response of niacin. Niacinamide increases ceramide and fatty acid levels in the skin to provide maximum hydration. Studies have shown that niacinamide hydrates, reduces transepidermal water loss (TEWL), and maintains hydration in the stratum corneum.
  • Panthenol a provitamin of b5 that helps restore barrier function and encourage post-treatment rejuvenation.


1. Facial Wash Oily/Problem – Cleanse the area of treatment thoroughly. Rinse and pat dry.


2. Smoothing Toner – Apply with a cotton pad to prep the skin. Allow the skin to dry. This product may sting or tingle on some individuals. Assess sensitivity by asking the patient, “On a scale of one to ten, ten being extremely active, how do you rate this sensation (or feeling)?”


3. Activator (Step 1) – Pour a generous amount into a small peel dish. Apply with a brush over the entire area of treatment. Allow to penetrate and dry thoroughly. The patient will feel internal warming as the skin is being stimulated. Fan the patient to keep them cool. You may proceed with the treatment once the product has absorbed and the patient’s skin is dry to the touch.

4. Detoxifier (Step 2) – Apply with your fingers in a circular motion over the entire treatment area. Take your time with massaging the treatment area. Wait three minutes to allow product to penetrate. Remove any obvious excess by gently blotting with a tissue or with Nutrient Toner on a cotton pad.


5. After performing the first two steps of this trio, customize the protocol with a combination of corrective daily care products to address your patient’s particular concerns and skin care goals.


6. Oxygenator (Step 3) – Massage a generous amount into the skin with your fingers in a circular motion over the entire area of treatment. A little of this product goes a long way, so do not overuse, avoiding contact with the eyebrows and hair due to possibility of bleaching. Coverage should be thin, even and thorough.

Retinoid booster (optional)

7. Advanced Treatment Booster – Dispense two pumps into gloved hands. Gently spread the product over the area of treatment, keeping application even and thin.

  • Use the scale of 1 to 10 to gauge sensitivity. Most patients will not have any sensitivity to this product.
  • The maximum number of layers is one.

Hydrate & protect

8. ReBalance and the appropriate PCA SKIN® broad spectrum SPF product – Complete the treatment with this combination to calm, hydrate and protect the skin from UVA and UVB exposure.

9. Hyaluronic Acid Lip Booster – Finish with a liberal application to improve hydration and reduce the appearance of lip lines.

Note: Apply the appropriate PCA SKIN® broad spectrum SPF product prior to applying Hyaluronic Acid Lip Booster to protect the lips from UVA and UVB exposure.